This research has numerous pros. A portion of the importance are it absolutely was all over the country, population-oriented, longitudinal with a take-right up time of at least two decades, and had a higher level from contribution (>90%). Also, the information and knowledge into the top, weight, socioeconomic updates and you may training (both in youth and also as people), and you may marital status was indeed accumulated out of populace-established documents for example were not self-said. Bmi try mentioned in the decades 18–two decades, prior to mature marital standing was firmly mainly based, avoiding the possibility of opposite causality [19, 20]. Men who had been ination was basically excluded to advance help it argument. But not, the first dimension of Body mass index can felt a limitation of your own investigation. The newest frequency out-of being obese was most probably large from the ages 29–40 years, resulting in some extent regarding misclassification prejudice. Although not, these types of prospective bias must have skewed the latest prices for the the brand new null hypothesis.